What levels need to be monitored regularly in patients taking Warfarin (Coumadin)?

The correct choice, which involves monitoring PT (prothrombin time) and INR (international normalized ratio), is crucial for patients taking Warfarin, a blood thinner used to prevent the formation of harmful blood clots. Warfarin works by inhibiting vitamin K-dependent clotting factors, which can vary significantly from patient to patient.

Monitoring PT and INR is essential because it helps ensure that the anticoagulation effect of Warfarin is within the therapeutic range, minimizing the risk of bleeding complications while also ensuring that the medication is effective in preventing clot formation. The INR is especially important as it standardizes PT results regardless of the testing method used, allowing for consistent management of Warfarin therapy across different laboratories.

Regular checks of PT and INR allow healthcare providers to adjust the dose of Warfarin as necessary, depending on the results. This is vital since various factors, such as diet, other medications, and the patient's overall health, can influence Warfarin's effectiveness and safety.

Monitoring other parameters like blood glucose, electrolytes, liver function, creatinine, heart rate, and respiratory rate, while important for overall patient management, does not specifically assess the anticoagulation status provided by Warfarin therapy, which is the primary